Methods

Collection and histopathological analysis of tumour samples

Only tumour samples collected before any treatment will be selected. Tumour samples are obtained from the Chris Hani Baragwanath Hospital, where the cases undergo biopsy or surgical resection. These specimens are fixed in fresh-buffered formalin and paraffin-embedded (FFPE) according to standard protocols. Paraffin blocks are kept at the local pathology service facilities under controlled storage conditions.