Methods

Storage, transportation, and shipment

For each subject, 10 1 mL aliquots of urine are stored, plus 20 0.2 mL aliquots of plasma, 20 of serum, 6 of buffy coat, and 6 of red blood cells.

This biological material will be used for measurements of markers of metabolism, somatic and germline mutations, epigenetics, nutritional biomarkers, hormones, and metabonomics to investigate the etiology of breast cancer in this specific setting.